This virus belongs to the herpes family and causes a condition known as infectious mononucleosis. Epstein-Barr has also been nicknamed "kissing disease" for it's ability to spread through oral contact. The name comes from the two scientists who discovered in 1964 that it causes mononucleosis.

In poor countries where hygiene is low, most children have been infected by the age of 6. However, at this early age, the disease is mild and even unnoticeable at times.